Isolation of Digeranyl From the Hexane Extract of Moringa Peregrina Leaves

Abstract

The plant kingdom provides many precious gifts to mankind. One of these gifts is its ability to produce an endless stream of natural products. Moringa peregrina (In Oman called Al Shua)  provides a wide range of benefits to traditional medicine in many cultures, as well many nutritional values. This paper discusses the isolation, and purification of digeranyl from the hexane extract of Moringa peregrine’s leaves, for the first time. Recent studies show that digeranyl phosphate derivative, digeranyl bisphosphonate, inhibits breast cancer cell migration by inhibiting geranylgeranyl diphosphate synthase (GGDPS). The structure of the isolated compound has been confirmed using different spectroscopic methods. 

  Keywords: Moringa peregrina; Omani medicinal plants; Diterpene; Digeranyl.