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Abstract

Objective: To describe the angiotensin converting enzyme (ACE) genotype frequencies among Omani Arabs. Method: A polymerase chain reaction (PCR) test, based on separation of different size DNA fragments, was developed to test the presence or absence (polymorphism) of a small DNA deletion in the ACE gene. The subjects were 124 Omani Arab students of Sultan Qaboos University, Muscat. Results: The frequency of the I allele was 0.29, while that of the D allele was 0.71. The gene frequency distribution did not deviate from Hardy-Weinberg equilibrium. Conclusions: The frequency of D allele among Omanis is similar to that among other Arabs and Africans, but differs significantly from that among the Japanese and Chinese. 

Keywords

Allele genotype polymorphism hypertension.

Article Details

How to Cite
Al-Hinai, A. T., Hassan, M. O., Simsek, M., Al-Barwani, H., & Bayoumi, R. (2002). Genotypes and Allele Frequencies of Angiotensin Converting Enzyme (ACE) Insertion/deletion polymorphism among Omanis. Sultan Qaboos University Medical Journal [SQUMJ], 4(1), 25–27. Retrieved from https://journals.squ.edu.om/index.php/squmj/article/view/1231