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Objective: To describe the angiotensin converting enzyme (ACE) genotype frequencies among Omani Arabs. Method: A polymerase chain reaction (PCR) test, based on separation of different size DNA fragments, was developed to test the presence or absence (polymorphism) of a small DNA deletion in the ACE gene. The subjects were 124 Omani Arab students of Sultan Qaboos University, Muscat. Results: The frequency of the I allele was 0.29, while that of the D allele was 0.71. The gene frequency distribution did not deviate from Hardy-Weinberg equilibrium. Conclusions: The frequency of D allele among Omanis is similar to that among other Arabs and Africans, but differs significantly from that among the Japanese and Chinese. 


Allele genotype polymorphism hypertension.

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Al-Hinai, A. T., Hassan, M. O., Simsek, M., Al-Barwani, H., & Bayoumi, R. (2002). Genotypes and Allele Frequencies of Angiotensin Converting Enzyme (ACE) Insertion/deletion polymorphism among Omanis. Sultan Qaboos University Medical Journal [SQUMJ], 4(1), 25–27. Retrieved from