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A 67-year-old man of Chinese descent presented with a painless nodular lesion that had been present on his right forearm for the previous 3 months. A single, well-defined, dome-shaped, firm nodule with a central keratin plug surrounded by erythema was noted. Keratoacanthoma with secondary bacterial infection was suspected and the patient underwent an excision biopsy. Biopsy of the nodule and immunohistochemical staining supported a diagnosis of nodular malignant melanoma. It should be noted both that nodular malignant melanoma may present with a wide variety of clinical appearances, and that the lack of melanin pigment in nodular malignant melanoma may hinder the diagnosis of this aggressive tumour.


Melanoma Malignant melanoma Keratoacanthoma Case report Malaysia.

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Muthupalaniappen, L., Das, S., Md No, N., & Ali, S. A. M. (2012). Nodular Melanoma Mimicking Keratoacanthoma : Lessons to learn. Sultan Qaboos University Medical Journal, 12(3), 360–363. Retrieved from

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