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Abstract

An extremely premature male neonate presented with an unusual multisystem dysfunction within the first 24 to 48 hours of life. The unfolding of clinical events and investigations revealed a transient myeloproliferative disorder (TMD). TMD was the main indication for karyotyping of this premature infant without clinical symptoms of Down syndrome. The awareness of TMD in a newborn warrants karyotype analysis to look for trisomy 21 and a close surveillance because of its potential progression to true leukaemia. 


Keywords

Extreme premature Transient myeloproliferative disorder Down syndrome GATA1 Acute myelogenous leukemia (AML) Case report Oman.

Article Details

How to Cite
Reyes, Z. S., Bashir, W., & Pathare, A. (2012). Transient Myeloproliferative Disorder and Down Syndrome Is there a link?. Sultan Qaboos University Medical Journal [SQUMJ], 12(4), 498–502. Retrieved from https://journals.squ.edu.om/index.php/squmj/article/view/1729