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Androgen insensitivity syndrome is a disorder of sex development resulting from mutations in androgen receptor. In complete form of this disorder, patients are genetically males, but phenotypically females, presenting with primary amenorrhea. We report three cases of Androgen Insensitivity Syndrome highlighting multifaceted role of MRI for presurgical planning by evaluating location, type of gonads and detecting possible complications. All patients presented with primary amenorrhea and MRI accurately localised testes in all, one patient had bilateral inguinal and two had intra-abdominal testes. Intra-abdominal testes were not localised on USG. MRI also depicted Sertoli cell adenomas and Wolffian duct remnants in these patients. MRI can provide comprehensive imaging prior to surgical treatment and thus can be considered a ‘One Stop Shop’ for imaging in androgen insensitivity syndrome. All the patients underwent laparoscopic gonadectomy which is the standard of care, with preoperative counseling about fertility. Postoperatively, they were started on estrogen therapy.
Keywords: Amenorrhea; Androgen-insensitivity syndrome; magnetic resonance imaging.

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How to Cite
Mukhopadhyay, I., Aggarwal, R., Mutreja, D., & Maheswari, S. (2021). MRI Findings in Androgen Insensitivity: Case series. Sultan Qaboos University Medical Journal [SQUMJ], 1(1).