Effect of Life-Style Modification Intervention Programme on Bone Mineral Density among Postmenopausal Women with Osteoporosis

Abstract

Objectives: Osteoporosis is one of the major public health problems worldwide among postmenopausal osteoporotic women. Lifestyle modification interventions along with pharmacotherapy helps to revert the bone loss and prevent the complications. Methods: A randomized controlled trial was conducted at Kasturba Hospital, Manipal from January 2019 to December 2021 among postmenopausal women with osteoporosis. The postmenopausal women who attended the osteoporosis clinic and were within the age group of 45-65 years, could speak and understand English or Kannada, and whose Bone Mineral Density (BMD) score was between -1 and -3 were included for the study. The total sample size of the study was 120 with 60 in each of the experimental and control group. After obtaining the informed consent, stratified block randomization method was used to allocate the participants to intervention and control group. The BMD was monitored by the portable ultrasound densitometer by a technician at the outpatient departments. The baseline information was collected by a structured demographic questionnaire. Intervention group participants received Lifestyle Modification Intervention Program (LMIP) whereas control group received the standard regular care by the physician.  Follow up was done at three and six months. Results: The results revealed that the increase in the BMD median score among the experimental group was from -2.2 [(-2.5, -1.8)] to -1.5 [(-1.8, -0.65)] where as in the control group it was from -2.3 [(-2.6, -1.9)] to -2.0 [(-2.4, -1.5)].  The increase in the median score of the experimental group (0.7) was higher than in the control group (0.3). The results of Mann Whitey U test showed a statistical significance between the intervention and control groups in the post test after 6 months (U =.505.5, p<0.05). Wilcoxon signed rank test showed the significant change in both the intervention and control groups from pre-test to post-test I (3 months) and Post-test II (6 months) (p<0.001). Conclusion: The lifestyle modification intervention was found to be effective in improving the bone health status of postmenopausal women. Hence it is very important to integrate in regular therapy.

Keywords: LMIP, postmenopausal women, bone health status, bone mineral density.