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Papilliferous keratoameloblastoma (PKA) is a rare entity, and not much is known about its clinicodemographic features or biological nature. This review aimed to provide clarity regarding the characterisation of the demographic, clinical, radiological and histopathological features of PKA. Case reports of PKA were identified through a systematic search across multiple databases. The search yielded a total of 10 cases, half of which were of Indian origin. All the cases invariably occurred in the mandibular posterior region and involved the right side; only one case primarily involved the left side of the mandible. PKA should be considered a variant of the conventional ameloblastoma that is towards the more aggressive end of the spectrum. It tends to occur in older individuals (in their fifth decade or older), with a marked propensity to occur in the right mandibular posterior region. Surgical resection with diligent follow-up is warranted in the treatment of PKA.

Keywords: Odontogenic Tumors; Ameloblastoma; Keratin; Odontogenic Keratocyst.

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Sachdev, S. S., Chettiankandy, T. J., Adhane, Y. B., Sardar, M. A., Trimukhe, A., & Jain, R. (2023). Papilliferous Keratoameloblastoma: Systematic review. Sultan Qaboos University Medical Journal, 23(3), 288–296.

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