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Trichodysplasia spinulosa (TS) is a unique, rare clinical and histological dermatologic entity described mainly in a setting of immunosuppression. It is caused by a novel human polymoavirus, TS-associated polyomavirus. Reduction of immunosuppression and/or anti-viral therapy is the main therapeutic strategies used to treat such cases. We report a biopsy-proven case of TS in a male renal transplant patient who presented to a dermatology outpatient clinic in Montreal, Canada, in 2015. He was managed with valgancyclovir with no obvious response. Subsequently, a trial of topical imiquimod was commenced. Awareness of TS can prompt early diagnosis and management to prevent possible complications.

Keywords: Immunosuppression; Organ Transplant; Human Polyomavirus; Case Report; Canada.

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Al Khalili, A., Maciagowski, E., Nguyen, K., & Watters, K. A. (2024). Trichodysplasia Spinulosa. Sultan Qaboos University Medical Journal, 24(1), 131–134.

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