Inclusion Body Myositis: Navigating diagnostic challenges, case report

Abstract

Inclusion body myositis (IBM) is a rare progressive myopathy affecting individuals older than 50 years. It is associated with significant morbidity once restricting the patient's mobility, and it has a relatively low mortality risk with respiratory muscles involvement. Muscle biopsy is the gold standard method for diagnosis. In this complex scenario, we present a case involving a 72-year-old woman admitted to our hospital with progressive weakness of lower limbs. The diagnostic process was challenging due to the case's complexity necessitating a multidisciplinary team approach. This case highlights the intricate nature of the diagnostic journey, as diagnosing IBM remains a challenge in clinical practice, requiring a high suspicion and precise application of available diagnostic tools with the guidance of a collaborative multidisciplinary approach in investigating and providing patient care. This case report contributes valuable insights to the understanding of this complex myopathy, facilitating more accurate diagnosis and enhancing patient care strategies

Keywords: Sporadic inclusion body myositis; idiopathic inflammatory myopathy; rimmed vacuoles