Chondromyxoid Fibroma of Phalanges

Abstract

Chondromyxoid fibroma (CMF) is a rare, benign metaphyseal bone tumour characterised by a combination of chondroid, myxoid, and fibrous elements, which can affect any bone at any age, without a gender predilection. We report the case of CMF in a 47-year-old lady who presented with swelling of the left little finger to a tertiary care hospital at Kolkata, India, in May 2024. Imaging showed presence of a lobulated lesion arising from the middle phalanx of the left little finger, extending to involve the base of the distal phalanx. Fine needle aspiration cytology of the lesion was indicative of a moderately cellular myxoid lesion. Histopathology remains crucial for diagnosis, which revealed a lobulated tumour with zones of spindle to stellate cells, associated with abundant myxoid and chondroid matrix in the intercellular areas. Treatment involves complete local excision with tumor free margins, as recurrence can occur with local curettage.