@article{Mohamed_Elmazary_Taha_2013, title={Ankle Brachial Index in Children with Steroid-Resistant Nephrotic Syndrome}, volume={13}, url={https://journals.squ.edu.om/index.php/squmj/article/view/1747}, abstractNote={<span><span>Objectives</span></span><span>: This study aimed to assess the ankle brachial index (ABI) as a predictor of peripheral arterial diseases (PAD) in children with steroid-resistant nephrotic syndrome (NS). </span><span><span>Methods</span></span><span>: Twenty children (11 males and 9 females) attending the Pediatric Nephrology Outpatient Clinic of El-Minia University Hospital, Egypt, were enrolled in this study. Their age ranged between 5 and 15 years with a mean of 10.75 ± 3.31 years. They had proteinuria and were dependent on steroid therapy. Twenty healthy age- and sex-matched children served as a control group. All patients and controls underwent a thorough history-taking and clinical examination. All subjects in the study underwent laboratory investigations, including a urine analysis (24-hour test for protein in urine, and levels of serum urea and creatinine, triglycerides, and cholesterol). A renal biopsy was done to diagnose the children’s histopathological type of NS. A Doppler study was done to determine patients’ ABI. </span><span><span>Results</span></span><span>: ABI was significantly higher in the patient group than in the control group (P <0.0001). There was a negative correlation between ABI and duration of treatment (r value = 0.77 and P <0.001). </span><span><span>Conclusion</span></span><span>: ABI is simple non-invasive manoeuvre that can reliably assess arterial stiffness as an early predictor of atherosclerosis in nephrotic patients with long duration of both illness and steroid therapy.</span><br /><br />}, number={1}, journal={Sultan Qaboos University Medical Journal}, author={Mohamed, Sheren M. and Elmazary, Abdelazem and Taha, Hany T.}, year={2013}, month={Feb.}, pages={88–92} }