TY - JOUR AU - Herrera-Acosta, Enrique AU - Martina, Gustavo Guillermo Garriga AU - Suárez-Pérez, Jorge Alonso AU - Martínez-García, Eliseo Alejandro AU - Herrera-Ceballos, Enrique PY - 2021/08/29 Y2 - 2024/03/29 TI - Ixekizumab for patients with plaque psoriasis affected by multiple sclerosis: A case report JF - Sultan Qaboos University Medical Journal JA - Sultan Qaboos Univ Med J VL - 21 IS - 3 SE - Case Reports DO - 10.18295/squmj.4.2021.021 UR - https://journals.squ.edu.om/index.php/squmj/article/view/4195 SP - 488-490 AB - <p>Multiple sclerosis is an autoimmune demyelinating disorder of the central nervous system that shares similar immunopathogenic mechanisms with chronic plaque psoriasis, such as the overexpression of the Th17 pathway. We report the case of a patient with multiple sclerosis and severe chronic plaque psoriasis successfully treated with ixekizumab (anti IL-17A and IL-17A/F monoclonal antibody). The treatment achieved a complete skin clearance (PASI 100 response) with no adverse events or evidence of progression of the neurological disease.</p><p><strong><em>Keywords:</em></strong> Psoriasis; Ixekizumab; Multiple sclerosis</p> ER -