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Compartment syndrome is a surgical emergency that could be resolved by a fasciotomy. However, performing substantial skin incisions may lead to life-threatening complications. This narrative review aimed to present the available methods of wound closure and preferential factors for using each technique. Viable and noninfected wounds were most often treated by gradual approximation techniques, such as the simple or modified shoelace technique, the prepositioned intracutaneous suture or several commercially-available mechanical devices. In addition, applying negative pressure therapy was found to be feasible, particularly when combined with approximation techniques. Skin grafting was reserved for severely-dehiscent wounds while other non-invasive approaches were considered for other subsets of patients with inadvisable surgical interventions. Treatment decision should be made in view of the patient’s condition, ease of application, availability of resources, cost of treatment and aesthetic outcomes.

Keywords: Compartment Syndrome; Fasciotomy; Wound Closure Techniques; Negative-Pressure Wound Therapy.

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How to Cite
Alkhalifah, M. K., & Almutairi, F. S. H. (2019). Optimising Wound Closure Following a Fasciotomy: A narrative review. Sultan Qaboos University Medical Journal, 19(3), e192–200.