All manuscripts are scanned at submission and during the review process by our anti-plagiarism software and the report generated is thoroughly examined by the Editorial Team. If there are minor similarities between the submitted manuscript and other sources, the authors are informed of this similarity and asked to amend their manuscript accordingly. If there is major misconduct, the manuscripts are rejected according to the guidelines of the ICMJE (International Committee of Medical Journal Editors) and COPE (Committee on Publication Ethics).